Vitamin K2: The Necessary Nutrient For Longevity (2024)

Vitamin K2: The Necessary Nutrient For Longevity (1)

I found myself enthralled learning about vitamin K2 after I started to experience teeth sensitivity when drinking hot or cold beverages.

My research into why this might be occurring led me down a rabbit hole – one that inevitably guided me into the fascinating world of vitamin K2.

From a well functioning heart to strong teeth and healthy bones, vitamin K2 is absolutely crucial.

Some experts think it’s the missing link for many people suffering from dental cavities (even those who brush and floss well), gum recession, osteopenia and osteoporosis.

That’s a big statement.

So…

What is Vitamin K

Vitamin K is one of the fat soluble vitamins (A, D, E are the others), meaning its bodily absorption happens after it has been dissolved in fat. Hence why most fat soluble vitamins contain some type of oil or other fatty carrier.

While similar structurally, there are three compounds that make up vitamin K, all beneficial for their own reasons – phylloquinone (vitamin K1), menaquinone (vitamin K2) and menodione (vitamin K3).

Vitamin K1 is the most common form and is primarily known for its ability to clot blood. A true deficiency of vitamin K1 would quickly lead to excessive bleeding from the smallest of cuts.

Coupled with vitamin D, calcium (and some believe magnesium too), vitamin K2 is believed to play an important role in cardiovascular health and the maintenance of strong bones, teeth and gums. (1)

What’s The Deal With MK4 and MK7

MK4 and MK7 are just two different chain-variations of the same vitamin (there are 9 in total – i.e. menoquiones-vitamin-k-4, menoquiones-vitamin-k-5, etc. (MK-4 and MK-5 are the shorthands).

The MK4 variant is commonly found in animal meat, liver, eggs and grass fed butter.

Because MK4 supplements are synthetic, it’s often suggested that this form of vitamin K2 come primarily from food sources alone.

The MK7 variant is the byproduct of fermentation.

This particular menoquione can be found in some cheeses and other types of fermented foods. The most common source is a Japanese soybean ferment called Natto. The species of bacteria (Bacillus subtilis) used in this fermentation produces high levels of MK7.

Unlike MK4, MK7 supplements are not synthetic, they are naturally extracted byproducts as a result of the fermentation process.

Vitamin K Benefits and Functions

Vitamin K2: The Necessary Nutrient For Longevity (2)

Vitamin K2 seems to be in the spotlight lately, and for good reason. The more we study this vitamin, the more fascinating the findings.

Some evidence suggests vitamin K2 may…

Improve Bone Density and Decrease the Chance of Developing Osteopenia and Osteoporosis.

Bones are meant to be strong, durable and impact resistant. They’re made up primarily of collagen and calcium (for strength and density).

Osteopenia is the beginning of bone density loss and weakness. If not addressed, osteopenia can eventually turn into osteporosis, or porous, brittle bones that are highly susceptible to fractures and breaks.

Evidence suggests that vitamin K2 stimulates an anabolic (or growth) response in bones. (2)

Improves the Health of Teeth and Gum Tissue.

The jawbone is linked to the periodontal ligament. When weakened, this bone can directly affect gums (recession) around the teeth.

One of vitamin K2’s functions is to stimulate the protein osteocalcin which funnel’s calcium out from the bloodstream and into appropriate areas of the body such as the bone and teeth. (3)

This process has a direct correlation to the health and ultimately longevity of teeth and gum tissue.

Likewise, a deficiency or low levels of this vitamin can, you guessed it, have the opposite effect.

Improve Cardiovascular Health and Reduce the Likelihood of Heart Disease

Atherosclerosis or arterial hardening is extremely dangerous. Symptoms are location specific, depending on which arteries have hardened. In the scariest of situations, a heart attack or stroke may occur.

Keeping arteries limber, unclogged and youthful are one of the keys to cardiovascular health.

There is some observational studies that imply vitamin K2 can actually prevent the buildup of calcification in the arteries. (4), (5), (6)

Vitamin K Foods

It’s not always possible to get our vitamin requirements from the food we eat, but I believe it’s still good practice to try.

Below I’ve listed some of the foods highest in vitamin K.

K1 Food Sources

Mostly green vegetables such as:

There are also small amounts of vitamin K1 in the skins of fruits and other vegetables too.

  • Swiss Chard
  • Collard Greens
  • Spinach
  • Kale
  • Turnip Greens
  • Brussels Sprouts
  • Brocolli

K2 Food Sources

  • Natto (fermented soybeans, highest source of MK7)
  • All meat (preferably grass fed)
  • Liver
  • Eggs
  • Cheeses
  • Some fermented vegetables (i.e. sauerkraut)

Vitamin K Deficiency – Signs and Symptoms

While it’s rare to actually have a true deficiency of vitamin K1, its K2 counterpart is a whole different story.

The belief used to be that our gut micriobiome could easily convert adequate levels of vitamin K1 into K2.

It’s beginning to appear this may not be entirely true as chronic deficiency of this vitamin is hard to pinpoint.

The symptoms manifest gradually, over the course of many years.

And the deficiency can show up suddenly as a cardiac related disease, a diagnosis of osteopenia or osteoporosis following a bone density scan, or fast paced oral decline (excessive gum recession, dental cavities).

Fortunately our body is resilient and very forgiving.

The best course of action to prevent and reverse a deficiency is to make it a habit to eat foods high in the vitamin and take a good quality vitamin K supplement.

Vitamin K Supplement – Should You Take One?

It’s entirely up to you.

Some people believe that we should get all of our vitamins from the food we eat.

While this sounds good and I, myself believe it in theory, it’s often not possible in the real world.

Sometimes things are just outside of our control, whether it be the cost of organic, the availability of food, taste and texture preferences (shout out to all the parents out there), leaky gut permeability, and so forth.

So supplements are necessary sometimes. Especially if your goal is to be as healthy as possible.

I’ve personally noticed a dramatic decline in my oral health over the last few years and in analyzing my diet, I came to the clear conclusion that I have probably been chronically low in vitamin K2 for years.

Therefore, I decided a supplement was wise for myself.

I figured if there was a way to protect my teeth, bones and ultimately heart, I wanted to jump at the chance to do so.

I would like to point out again that all vitamin K2 MK4 supplements are synthetic. If you decide to take one, I advise that you stick with an MK7 version.

Take note of this study that concluded MK7 supplementation was not only absorbed better but also supplied the body with a higher level of MK4 (after bodily conversion) than a straight MK4 supplement (7)

After much deliberation, this is the vitamin K supplement I chose and currently take. Use the discount code holfam10 to save an additional 10% off.

Wrap Up

Science is beginning to understand just how paramount vitamin K2 is to human health.

Where calcium ultimately ends up in our bodies can be a large contributor to our overall health – specifically our heart, bones and teeth.

Vitamin K2 is the driver of that decision. It activates osteocalcin which directs where calcium should and should not go (away from our arteries and into our bones and teeth).

A chronic deficiency of this vitamin can be detrimental to our health; it’s good practice to try and incorporate as many vitamin K rich foods into our diets as possible and possibly supplement for an ongoing and ideal level of health.

Vitamin K2: The Necessary Nutrient For Longevity (2024)

FAQs

Does vitamin K2 increase life expectancy? ›

Often age-related, the risk for cardiovascular and bone disease increases as life expectancy rises. Vitamin K2 could therefore help to tackle an important challenge in global health, that is to live a longer and healthier life.

How much vitamin K2 for anti aging? ›

The scientists studying the effects of vitamin K2 suggest the potential benefits come with a daily intake of between 10 and 45 micrograms. It has been observed that about 90% of vitamin K consumed in the average diet is K1.

Is vitamin K2 really necessary? ›

It's essential to many aspects of your health, including blood clotting, calcium metabolism, and heart health. Some think vitamin K2 may be the missing link between diet and several chronic diseases.

What happens if you take vitamin K2 every day? ›

Some early research has shown that vitamin K2 may be more effective at clearing out calcium than vitamin K1. One study found that people who took in at least 32 micrograms per day of vitamin K2 in their diet were 50% less likely to die from heart disease related to hardened arteries.

Does vitamin K2 really clean arteries? ›

Increased vitamin K2 intake may reduce arterial stiffness, slow progression of vascular and valvular calcification, lower the incidence of diabetes and coronary artery disease, and decrease cardiovascular mortality.

Are there any dangers of taking vitamin K2? ›

When taken by mouth: The two forms of vitamin K (vitamin K1 and vitamin K2) are likely safe when taken appropriately. Vitamin K1 10 mg daily and vitamin K2 45 mg daily have been safely used for up to 2 years. It's usually well-tolerated, but some people may have an upset stomach or diarrhea.

How much vitamin K should a 70 year old take? ›

How much vitamin K do I need?
Life StageRecommended Amount
Adult men 19 years and older120 mcg
Adult women 19 years and older90 mcg
Pregnant or breastfeeding teens75 mcg
Pregnant or breastfeeding women90 mcg
6 more rows
Mar 22, 2021

Who should not take vitamin K2? ›

People with a rare metabolic condition called Glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid vitamin K. People who take warfarin (Coumadin) should not take vitamin K (see “Possible Interactions”). People who are receiving dialysis for kidney diseases can have harmful effects from too much vitamin K.

What is the most absorbable form of vitamin K2? ›

MK-7 is a form of vitamin K2 that has greater bioavailability than MK-4 after oral administration,4 but the therapeutic utility of MK-7 in RA had not been investigated previously.

Should I take D3 and K2 at the same time? ›

Vitamins D and K are two supplements your healthcare provider might say you need. Products that combine the two usually include the D3 and K2 forms of the vitamins. If you need to take both, it is likely safe to do so. In fact, together, the two might be even more beneficial for bone health.

Does apple cider vinegar have vitamin K2? ›

The K2 form is missing in most food sources. It is found mainly in fermented foods such as sauerkraut, kefir, apple cider vinegar, and natto.

Is it OK to take K2 without D3? ›

The reason why you want to take these two vitamins together is because they offer your body more benefits when combined. In fact, they work together within the body: vitamin D3 directs the absorption of calcium from your intestines into the blood. Vitamin K2 takes it from there, directing that calcium into your bones.

What depletes vitamin K2? ›

What non-dietary factors can cause Vitamin K2 deficiency?
  • Current antibiotic use.
  • Long-term antibiotic use.
  • Following a low fat diet.
  • Fat malabsorption conditions.
  • Fat blocking pills (commonly marketed as weight-loss supplements)
  • Some cholesterol-lowering drugs.
  • Dilantin use during pregnancy.
  • GI tract diseases.
Sep 25, 2020

When should I take vitamin K2 morning or night? ›

Vitamin D3 and K2 are best taken together for optimal absorption, and supplementing them with breakfast or lunch is ideal because this is when your body would be synthesizing D from sun light. E is fine to take at any point throughout the day. Magnesium is ideal if taken at night as it can aid with digestion and sleep.

How much K2 should I take with 5000 IU/D3? ›

For every 5,000–10,000 units of D3 being recommended and tested for, we are recommending 100 mcg of K2 mk7 to be sure and prevent the inappropriate calcification that higher doses of D3 alone could cause.

How long does it take for vitamin K2 to reverse calcification? ›

In the groups receiving high-dose vitamin K1 or K2 (MK-4), not only was there no further arterial calcium accumulation, there was a 37% reduction of previously accumulated arterial calcification after six weeks. After 12 weeks, there was a 53% reduction in accumulated arterial calcium deposits.

Is vitamin K2 safe for kidneys? ›

Standard in-center hemodialysis itself can cause organ stunning. Vitamin K2, a long misunderstood fat-soluble vitamin holds great potential for treating and preventing these conditions. In fact, a lack of vitamin K2 among CKD patients is likely a major risk factor leaving people vulnerable to these diseases.

Does K2 affect your kidneys? ›

The activity of MGP depends on γ-glutamyl carboxylase that converts inactive ucMGP to active cMGP, and vitamin K2 is a cofactor of this reaction. Deficiency of vitamin K2 leads to increase in the level of dp-ucMGP, which also rises with the deterioration of kidney function.

References

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